Sentence examples for mutant phenotypes using from inspiring English sources

To facilitate comparison and integration of phenotypes across organisms, model organism communities have spearheaded the representation of mutant phenotypes using ontologies and formal semantics [7].

This approach used competitive fitness of many strains in parallel; scoring mutant phenotypes using a PCR readout.

Future studies that systematically characterize genes and mutant phenotypes using targeted mutagenesis (e.g., P element insertions) or deletion mapping will further illuminate the connection between molecular and phenotypic sexual dimorphism.

Successful transgenic dog-1 gk10) dog-1 gk10re tested for rescue of dog-1 mutanimalsnotype using the deletion frequency of the G/C tract in gene vab-1 [ 19].

Therefore, we aimed to analyze metabolism and gene expression in sesB flies and to test different strategies to compensate the mutant phenotype, using similar approaches as those used previously for tko 25t.

Once a mutation is identified, the affected gene must be confirmed by a second mutation, perhaps by a gene knockout, or by a rescue of the mutant phenotype using a transgene.

In previous work on PhenoDigm, we have shown that the manually curated OMIM HP annotations can be used in cross-species semantic comparisons to mouse mutant phenotypes annotated using the Mammalian Phenotype Ontology (MP) (6).

To facilitate browsing of all phenotype information, the entire YPO hierarchy of observables is displayed on a web page on which each term is linked to the complete list of mutant phenotypes annotated using that observable (http://www.yeastgenome.org/cache/PhenotypeTree.html).html

We also tested directly whether the variants identified by BSA-seq in YPW89, YPW94, and YPW102 were responsible for their mutant phenotypes by using site-directed mutagenesis to introduce each candidate mutation individually into the genetic background carrying the P TDH3 -YFP transgene that was originally used for the EMS mutagenesis screen.

This could be most simply achieved using RNAi (though the phenotypes are arguably weaker than Rye mutants), selective rescue of Rye phenotypes using the UAS-Rye transgene, or perhaps even attempting to test if strong Rye over-expression in neuronal subsets might induce sleep (due to either stronger over-expression than Rye-GAL4 or a circuit-specific effect of Rye elevation).

The GPCR mutants also were tested for nutritional phenotypes using 60 × 15-mm VM agar plates.