Sentence examples for mutant phenotypes indicate from inspiring English sources

Our biochemical data and the analysis of mutant phenotypes indicate that ALS8 is due to DVAP loss-of-function, with Sac1 being downregulated and PtdIns4P levels subsequently increasing.

Functional studies using mouse Sox B1 genes to rescue fly mutant phenotypes indicate that the mammalian proteins are functionally related to both Dichaete and SoxN[ 12, 13].

Although a partial FIL transcript is produced by the fil-9 allele, the mutant phenotypes indicate that the T-DNA insertion most likely results in FIL loss-of-function and does not cause a dominant negative effect.

The genetic isolation of the FuI population and the predominance of early non-lethal mutant phenotypes indicated that the genetic variants responsible for the phenotypic variation are maintained due to population isolation.

This model is supported by evidence that elg1 deletion exacerbates mcd1 mutant phenotypes, indicating that Elg1p function is critical for the ultimate maintenance of sister chromatin pairing.

All injected animals developed the typical tra mutant phenotypes, indicating that with the RNA supplement, only the larval phenotype could be rescued (data not shown).

However, mutant strains containing ndd1 mutant alleles lacking the Pkc1 phosphorylation sites did not fully re-capitulate the pkc1 mutant phenotypes, indicating that additional defects are associated with loss of Pkc1 activity.

The failure of IBR5C129S to fully restore ibr5-1 mutant phenotypes indicates that IBR5 phosphatase activity is required for full auxin and ABA responsiveness, and it will be interesting to learn if any of the MAP kinases implicated in hormone responsiveness are IBR5 substrates.

Analyses of multiple aspects of the pygopus mutant phenotype indicate that this gene is dedicated to, and required for, canonical Wnt signaling during Drosophila development [ 9].

The interaction between the sol genotype and mutant phenotype indicate that sol impacts phenotype within the IBM x Lgn-R/+ individuals to a greater degree than in lgn wild-type siblings.

Moreover the mel1 mutant phenotype indicates that the MEL1 AGO protein mediates the regulation of germ-line mother cell development and meiosis in both male and female organs, suggesting that the MEL1-phasiRNA complexes may be involved in these processes (Nonomura et al. 2007; Komiya et al. 2014).