Sentence examples for mutant phenotypes including from inspiring English sources

Multiple candidate genes for aging have been identified in model systems by extended longevity mutant phenotypes, including the G-protein coupled receptor methuselah (mth) in D. melanogaster.

Spt5 with both CTR1 and CTR2CT deleted (NSpt5) not only failed to rescue fogs30 mutant phenotypes, including the body shape, brain morphology, eyes, heart, and blood circulation, but also exacerbated them.

The results show that defects in rRNA modification produce allele specific mutant phenotypes including increased sensitivity to translational inhibitors; defects in virus propagation; changes in translational fidelity as monitored by +1 and −1 PRF, discrimination between cognate- and near-cognate aa-tRNAs, and recognition of termination codons.

Increased dosage of NAB3 was found to suppress a subset of esa1 mutant phenotypes, including temperature sensitivity and silencing defects.

Furthermore, mTORC1 activation is essential downstream of APC as mTORC1 inhibition partially rescues Apc mutant phenotypes including early lethality, reduced circulation and liver hyperplasia.

DOI: http://dx.doi.org/10.7554/eLife.00190.007 Expression of APA-2 GFP APA-2 GFPiqunders promoter can fubiquitouse the mutant promoteres incanding the cuticle protrusions.

These non-redundant mutant phenotypes include increased spontaneous mutation rate, transient accumulation of cells in a mid-anaphase checkpoint after exposure to camptothecin and, in cells that overexpress topoisomerase I (Top1), decreased survival of camptothecin-induced damage.

Additional mutant phenotypes included squashed vulva (Sqv), and reduced L4 vulva invagination.

A mutant with a deletion of XAC3225 has reduced ability to cause canker (mutant phenotypes include a reduction in water soaking, hyperplasia, and necrosis compared to wild type) [ 31].

Thus, a single extra copy of either the Chc+ gene or the lqf+ gene suppressed the aux mutant phenotype, including lethality, significantly.

The cell wall is directly involved in several processes related to the cpr5 mutant phenotype, including both cell expansion and pathogen responses [ 16].