Previous studies have described Drosophila neurexin mutant phenotypes in third instar larvae and adults.
The insertions were homozygous viable, and did not cause any observable mutant phenotypes in the absence of GAL4 induction.
Mutant phenotypes in the axon scaffold were scored and at least three replicates were analyzed using a Student's t-test.
We set out to explore similarities between lam mutant phenotypes in Drosophila and laminopathic diseases in man.
Mutant phenotypes in mammals and flies suggest that caspases can also play important non-apoptotic roles, and the functions of some caspases are still unclear [9].
We independently showed that antioxidants delayed the onset of mutant phenotypes in ERG and improved larval vision function in phototaxis assay.
In this way, it differs from the closely related Phenote software, which is commonly used for EQ annotation of mutant phenotypes in the genetics community [4].
They applied a systems dynamics-based approach and bifurcation diagrams to provide a new perspective on cell cycle checkpoints and mutant phenotypes in fission yeast.
To examine the mutant phenotypes in further detail, we performed H&E staining of serial sagittal sections of E5.5, E6.5 and E7.5 embryos (Figure 2).
Several years ago, we published the first sequence-based map of genes with mutant phenotypes in Arabidopsis, which we concluded would eventually replace the classical genetic map [14].
However, several genes affecting FLC, including ASHH2, ATX1, ELF7 and ELF8, display additional mutant phenotypes, in plant size, flower morphology and/or fertility [8], [10], [11].
