Sentence examples for mutant phenotypes derived from inspiring English sources

Hence, a complexity arises in defining mutant phenotypes derived via knockout, RNAi depletion, point mutation, insertion etc, highlighting the need for caution in direct comparisons.

Proline-using mutant phenotypes in strains derived from RT244 were mapped by meiotic crossing to RT250 (yA1 pabaA1 pyrgpdAgpdareAHAreAHA fmdS-lacZ prn-309).

Page-McCaw et al. [22] noted that Drosophila MMP-1 mutant phenotype resembles the phenotype derived by mutation of Decapentaplegic (Dpp) supporting the hypothesis that MMPs may modulate the morphogen gradient directly or indirectly by degrading extracellular matrix proteins.

Nordström et al. [ 39] furthermore demonstrated that mutation identification is feasible even without relying on any kind of recombination by searching for common genes that are disrupted in two different mutants with the same phenotype derived from the same mutagenesis screen.

This model derives from mutant phenotypes of the third stage larvae (Casal et al., 2006; Donoughe and DiNardo, 2011) and experiments in which the distribution of Ds was manipulated, also at later stages (Repiso et al., 2010; Donoughe and DiNardo, 2011).

This review discusses the strategy employed to identify these genes as well as the conclusions about GABA transmission derived from study of the mutant phenotypes.

When evaluating experimental results from mice of specific strains or stocks or attempting to characterize phenotypes of mutant mice derived from them, it is important to be aware of the background pathology or phenotypes in order to determine if lesion incidences are increased or decreased compared to what occurs in non manipulated or wild-type animals of the same strain or stock.

The highly contrasting phenotypes as observed between two single mutants and double mutant derived from their inter-crossed progeny are unique.

Supplementary Figure 10 Scoring mutant phenotypes resulting from promoter competition.

Here we report the molecular genetic characterization of the first axolotl mutant phenotypes.

Fig. 7: TdHMA3-B1a complements Cd- and Zn-sensitive mutant phenotypes of yeast.