Sentence examples for mutant phenotypes characterize from inspiring English sources

The mutant phenotypes characterize the consequence of disturbing or disrupting the information output of a gene and thus are ideal to aid understanding of how genes function at the systems level.

We used transcription activator-like effector nuclease gene disruption technology to generate founder animals with mutations in the TRα gene and bred them to produce F1 offspring with a normal phenotype and a mutant phenotype, characterized by precocious hind limb development.

As a result, BR biosynthetic and response mutants exhibit phenotypes characterized by severe growth deficiencies.

Mutant phenotypes are characterized by changes in both the density of both CENP-ACnp1−containing nucleosomes and enrichment of H3K9me3 modifications.

Most of the target genes validated in this study were transcription factors, and their mutant phenotypes were characterized in many model plants (Table  4).

In Drosophila, notch pathway mutants have neurogenic phenotypes characterized by an excess of neuronal cells (Campos-Ortega, 1985).

Lastly, an examination of rpb1-12XS7ECTD mutants revealed morphological phenotypes characterized by the appearance of highly elongated cells with multiple septa and in some instances, "tea -like branching.

The ZZ mutant phenotype is characterized by a ∼80% reduction of the protein in plasma, which subsequently causes lung emphysema (Stoller and Aboussouan, 2005).

The first, larger, class of the CSN5-mutant phenotype was characterized by the reduced number of dendritic ends.

Thus, we demonstrate that the use of previously characterized mutant phenotypes and known roles of pathways in zebrafish embryogenesis can expedite the identification of molecular targets of small molecules.

Out of these 46 vps mutants, 13 mutants displayed a similar phenotype, characterized by an exaggerated prevacuolar organelle (aberrant endosomes) called the 'class E compartment'.