Sentence examples for mutant phenotype in from inspiring English sources

To further prove that the lack of TCM5 was responsible for the mutant phenotype in the tcm5 mutants, genetic complementation was performed.

Analysis of the mutant phenotype in mice carrying a targeted disruption of the Wnt5a locus shows distinct abnormalities in distal lung morphogenesis as manifested by distinct truncation of the trachea and overexpansion of the distal respiratory airways.

Several intrabodies that bind on either side of the expanded polyglutamine tract of mutant HTT have been reported to improve the mutant phenotype in cell and organotypic cultures, fruit flies, and mice.

The reason for the 'rescue' of the mutant phenotype in vivo and in vitro was the very rapid expansion of β1 integrin expressing keratinocytes in hpm skin.

In this sense, the hpaC mutant phenotype in Xcv is similar to that observed for yscP, invJ and spa32 mutants (see above).

The strong reduction in MAP4K3 levels observed upon the expression of interference RNA is not associated with any mutant phenotype in the adult wing (Fig. 2A B).

Roberts et al., [32] demonstrated that the VEGFR1 mutant phenotype in embryonic stem cell-derived blood vessels could be rescued by incubation with small molecule inhibitors of VEGFR2.

This architecture and the nature of the side-chain exchange may explain the lack of a mutant phenotype in sub-11.

Exogenously supplied NTD125 thus possessed a chaperone-like activity that activated p53 and could be of significance in restoring p53 mutant phenotype in cells under stress.

Since Mib1 is also expressed in IFE and hair follicles and regulates the endocytosis of Jag1 [14], [14], we examined whether conditional inactivation of Mib1 in the skin also reproduces the Jag1 mutant phenotype in the skin.

As NTD125 could activate p53 signaling pathways in cells by activating its downstream genes; it would be of interest to explore the conversion of p53 mutant phenotype in to the wild type in cancer cells.