Sentence examples for mutant patients failed from inspiring English sources

However, a recent large study in 505 Caucasian patients that included 167 KRAS mutant patients failed to find a difference in either PFS or OS [24].

For the patients diagnosed as WT by direct sequencing and treated with cetuximab (n=47), a response rate of 16.0% was observed for 38 ARMS/S WT patients, whereas 9 ARMS/S mutant (MUT) patients failed to respond.

Interestingly, there did appear to be small subset of KRAS mutant patients who failed to benefit from chemotherapy.

Given that some BRAF-mutant melanoma patients fail to respond to BRAF inhibitors, and that the majority of patients who do respond to BRAF/MEK inhibitors eventually develop resistance, there is an urgent need to identify possible combination treatments that may be effective.

In a report by Heimberger and colleagues, 42.6% of GBM patients failed to express EGFR, 25.9% had an overexpression of wtEGFR and 31.5% expressed a specific EGFR mutant (EGFRvIII, also known as EGFR type III, de2-7, ΔEGFR) [ 2].

Of these, 99 patients failed medical management.

No patient failed within a week of starting ADINA, although several patients failed to tolerate NCPAP.

Most patients failed to thrive.

Overall, 28 (22%) patients failed the postoperative VT.

All patients failed initial conservative management.

Five patients failed screening.