Sentence examples for mutant p53 containing from inspiring English sources

* Fold change is relative to mutant p53 containing tumors, i.e., all of these probes were elevated in wild type.

As further evidence for the p53-independent role of Mdm2 in estrogen mediated proliferation, we demonstrated that knockdown of Mdm 2 inhibited estrogen-induced proliferation of the mutant p53 containing cell line T-47D.

It will be especially interesting to examine transcription coupled repair efficiency following photolyase treatments in wild-type and mutant p53 containing cells as reports have indicated that transcription coupled repair efficiency can determine cell cycle progression and apoptosis in UV-irradiated cells [28].

* Number of probes used for prediction modeling from Table 2 ** The intersection of the top 100/1000 probe sets from early and advanced cancers * Mean fold change is relative to mutant p53 containing tumors Mutations in the p53 gene are extremely common in epithelial ovarian cancers, particularly those with serous histology.

The resulting mutant (T187C, containing two 187 187 disulfide bridges in the tetramer) showed a 200-fold increase in half-life at 75 °C and an increase of 15 deg.

Cyanogen bromide (CNBr) and enzymatic footprints of the photo-labelled receptor and an engineered receptor mutant (L113M), containing an additional CNBR cleavage site, allowed the photoreactive region to be identified as ORL1[107 113] at the C-terminal of TM helix II.

In this study we present a structural and functional comparison between MNEI and a sweeter mutant Y65R, containing an extra positive charge on the protein surface, in conditions mimicking those of typical beverages.

Compared with the empty-vector (pET21a) and predicted protonation-site mutant D407N containing strain, the wild type AcrB constructed in pET21a showed apparent resistance against ciprofloxacin.

The results of replicase assays performed with mutant VP2 containing a deletion in its RNA-binding domain suggests that the essential role for VP2 in replication is linked to the protein's ability to bind the mRNA template for minus-strand synthesis.

Because the L234K and C243A mutations are both located within β2 that appears distorted in these structures, we also constructed a mutant A3G containing both these mutations.

Female mice with cardiac-specific overexpression of mutant HSPB5 containing the R120G mutation, driven by the α-myosin heavy chain promoter, have been described previously [8].