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Whether the animal is a mammal unknown to science (something almost unheard of), a variant or mutant, or a species outside its normal range, are all open questions.
Remember all those sci-fi movies where the heroes were stuck in a terrible world where everybody but them was a mutant or a pod person or a hologram and their only hope was to reach a legendary and possibly mythical refuge?
In contrast, none of the human PP6Rs were capable of restoring normal eIF2α phosphorylation levels in either a quadruple sap mutant or a sap185 sap190 double mutant strain.
Similarly, in several instances agonist-induced internalization of a given GPCR has been shown to promote internalization of either a disabled mutant or a different GPCR altogether [7], [8], [9], [10], [11].
To investigate the virulence of the double mutant, SCID mice were injected intravenously with 105 CFU of either wild-type M. tuberculosis (strain H37Rv), a ΔsecA2 mutant, or a double mutant strain ΔsecA2ΔlysA.
In the current study, we found that PFO production by CPJV501 could be restored by coincubating CPJV501 with either a strain 13 pfoA-null mutant or a C. perfringens type C CN3685 pfoA-null mutant, both of which retain an intact agr locus (Fig. 6A and 6B).
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Chemical diversity was generated by in vitro chemoenzymatic and in vivo whole cell biocatalytic syntheses using either a B. bassiana mutant or an E. coli strain expressing the bbBeas gene [126].
We showed that LHP1 binding can be associated with a silent (i.e. in lif2 mutant) or an active (i.e. in WT) transcriptional status of FLC locus suggesting that LIF2 and most probably other components can modulate LHP1 activity.
The roles of soluble sugars and the glucose-6-phosphate/phosphate translocator2 (GPT2) in the altered acclimation response of adg1-1/tpt-2 to high light has been addressed by feeding sucrose or glucose to the double mutant or an adg1-1/tpt-2/gpt2-1 triple mutant.
Each allele, under the control of an arabinose-inducible araBAD promoter, was inserted in single copy into a neutral site of the chromosome of a lasR, rhlR mutant or an rpoS mutant, respectively.
First, we analyzed the expression of K3 during lytic replication by infection of NIH3T3 cells with parental virus, the Delta 40 bp mutant or, as a control, with a mutant lacking the 100 bp repeat (H. Adler et al.; unpublished).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com