Sentence examples for mutant of histone from inspiring English sources

We used a K12C mutant of histone H4 in our studies for targeted biotinylation of position 12, while in vivo only lysine residues are biotinylated.

Deletions of brl1 and shf1 (brl1∆ and shf1∆) abolished ubiquitination of histone H2B as did a lysine to arginine mutant of histone H2B in which the ubiquitin acceptor site is lost htb1-K119RR).

Here, we used the knockdown and mutant of histone H3 to explore the role of histone H3 phosphorylation at Ser10 in regulating LMP1-promoted cell transformation of CNE1 cells.

We did not detect any dominant effects at the level of growth rates or any of the tested phenotypes in yeast harboring both the wild type and any mutant version of histone H3 (Figure 1).

The knockdown and mutant (S10A) of histone H3 suppressed LMP1-induced CNE1 cell proliferation, foci formation and AP-1 activation.

The ibm1 mutation induces a variety of developmental abnormalities, which are suppressed by mutants of the histone H3K9 methylase KYP/SUVH4 gene and CHG methylase CMT3 gene.

In hip3-1 mutantseveralral modifications of histone H3 were aberrant at the SPCC663.14c+ promoter.

In homozygous tbrd-1 mutants, hyper-acetylation of histone H4, disappearance of histones as well as the occurrence of DNA breaks was not obviously altered (data not shown).

A series of azobenzenealkylmaleimides (AMDs) with different spacer length was synthesized and coupled via Michael-Addition to a specific mutant of a bacterial histone deacetylase-like amidohydrolase (HDAH).

clr6-1 is a loss of function mutant of Clr6, a histone deacetylase (HDAC) and known transcriptional repressor, which is similar to HDAC1/2 in higher organisms [16] [17].

To investigate the role of the Rsc and Bdf1 bromodomain-containing proteins in activation of cryptic internal transcription, we exploited a mutant of the Rpd3S histone deacetylase complex, rco1Δ, which has an ORF hyperacetylation phenotype.