Sentence examples for mutant mouse strains from inspiring English sources

It has also bred 5011 mutant mouse strains that have germ line transmission of the knockout.

The Merck team tried the compound in two mutant mouse strains that have classic diabetes symptoms.

Some of these mutant mouse strains were found to exhibit behavioral abnormalities reminiscent of human psychiatric disorders.

In order to address how DSCAM facilitates retinal pattering, we developed a conditional allele of Dscam to use alongside existing Dscam mutant mouse strains.

And she is a key player in a transnational consortium of research groups that are working to characterize mutant mouse strains, a European Union initiative called EUMORPHIA.

The observed increase in weight reflected an increased fat deposition for all mutant mouse strains.

One of the experiments that he is willing to divulge--which he calls a "bread and butter" project--involves a mutant mouse strain that develops a disease similar to human amyotrophic lateral sclerosis, or Lou Gehrig's disease.

Previous evidence implicating agouti in weight control comes from a naturally occurring mutant mouse strain that produces agouti in all its tissues, with the result that it not only becomes obese but also develops diabetes as a result of insulin resistance.

To knock out the gene only in breast tissue, teams led by Chu-Xia Deng and Lothar Hennighausen at the National Institute of Diabetes and Digestive and Kidney Diseases engineered a mutant mouse strain so that a molecular scissors would slice out the genetically tagged BRCA1 gene--but only in cells in the breast lining the milk ducts.

This study identified and characterized a mutant mouse strain with a novel ENU-induced mutation in the Scarb1 gene (I179N).

Several mouse models for MDC1A exist (e.g. generated LMα2 chain mutants dy3K/dy3Kand dyW/dyW and the spontaneous mutant mouse strain dy/dy) and they adequately mirror the human condition [2] [4].