Sentence examples for mutant mouse spleens from inspiring English sources

Flow cytometric analysis demonstrated that macrophages numbers were not reduced in mutant mouse spleens.

One study demonstrated that upregulation of several pro-apoptic genes in the spleen of Clock mutant mouse (Gaddameedhi et al., 2015).

RT-PCR confirmation of the mutation was performed on RNA extracted from kidney and spleen of both a homozygous mutant mouse and a wildtype littermate.

The first was a mutant mouse that lacked all its rods and 95percentt of its cones.

Cui decided to breed the mutant mouse.

Mouse spleens were carefully crushed to release the lymphocytes.

Leukocytes were isolated from 8-week-old mouse spleens.

We thank Cara Westmark for providing mouse spleens and thymus.

Specifically, spleens of mutant mice exhibited a 35% decrease in helper T cells (CD4+), a 22% decrease in CD3e+ T cells, a 24% decrease in CD5+ B and T cells, and a 35% increase in T regulatory cells (CD4+/CD25+)).

B220+ DN T cells are angeric [28] and are not actively proliferating in the lymph nodes and spleen of mutant mice but were reported to be proliferating in the liver of MRL/lpr mice [29].

By screening for the molecular events involved in the observed phenotypes, we found that lambda 5 expression is downregulated and its upstream inhibitor Aiolos is increased in the spleen of mutant mice, accompanied by significantly enhanced phosphorylation and nuclear translocation of cAMP response element-binding protein.