Sentence examples for mutant mouse lines from inspiring English sources

and S.O., provided the mutant mouse lines.

We discovered that this allele has actually been inadvertently backcrossed into multiple mutant mouse lines, including two engineered to be deficient in Siae and Cmah.

In recent issue of Nature, Adams and colleagues performed a genome-wide in vivo screen of 810 mutant mouse lines to identify important metastatic regulators in host microenvironment (van der Weyden et al., 2017).

C57BL/6J is one of most commonly used inbred strains of mice, especially as a genetic background in mutant mouse lines [31], [32].

In other mutant mouse lines referenced here [23], [30], [34], [35], [36], the responsible genes encode Wnt antagonists that repress Wnt transcription or the Wnt response.

We thank the phenotypic analysis groups at Lexicon Pharmaceuticals, Inc. for carrying out the comprehensive clinical diagnostic tests on the mutant mouse lines.

The new mutant mouse lines described here were used to address the following questions: i) is PiT1 essential for embryo development?

Hence we conclude that aggregation is an efficient and accessible method for the generation of chimeras for establishing new mutant mouse lines from B6 ES cells.

We kindly thank the members of the German Mouse Clinic for comprehensive phenotyping of the mutant mouse lines and fruitful discussions and Dian Soewarto for scientific discussion.

In summary, the large collection of symptomatic double-mutant mouse lines has greatly expanded the armory of potential mouse models for preclinical studies.

In this study, we combined the iTRAQ technique with the use of α4 and β2 nAChR subunit null-mutant mouse lines (these null-mutants express no functional α4β2 nAChRs [4,25] and heterozygotes express intermediate levels [26]).