Sentence examples for mutant mimicked the from inspiring English sources

We can conclude that the S270E nSmutantmimickedimicked the phosphorylated enzyme, leading to induced ceramide generation and apoptosis.

Overexpression of wild-type β-catenin or a constitutively active β-catenin mutant mimicked the effect of LTD4 on ATP/ADP ratio and mtDNA transcription.

The Δ core mutant mimicked the tir mutant in its ability to cause TER decrease (Fig. 5A, P = 0.7), suggesting the above described effectors were not involved.

An NPR2 deletion mutant mimicked the phenotypes produced by a GTP-bound Gtr1 mutant with respect to both autophagy and Tor1 localization, suggesting that Npr2-Npr3 reGTPates GTP hydrolysis in Gtr1.

The expression of the UCP3RE171/172GG mutant mimicked the effect of an overexpression of wild-type UCP3 only upon the addition of low Ca2+ while its effect was reduced upon the addition of middle and completely lost upon the addition of high Ca2+ (Fig. 6A and B).

BIC-induced proteasome activation in neurons was abrogated by CaMKII inhibitors, whereas the constitutively active T286D mutant (mimicking the autophosphorylated form) of CaMKIIα was sufficient to increase proteasome activity in both neurons and 293T cells.

However, sAPPα levels further increased when cells expressed a mutant mimicking the phosphorylation of SAP97 at T629 (YFP-SAP97-T629D), but not at S642 (YFP-SAP97-S642D), indicathat T629 T629 phosphorylation specifically boosts ADAM10 activity.

Both chimeras, i.e. UCP2UCP1 and UCP3UCP1, had no effect on mitochondrial sequestration of intracellularly released Ca2+ while these UCP mutants mimicked the effects of the wild-type isomers regarding a strong enhancement of mitochondrial uptake of entering Ca2+ (Fig. 1C).

We found that nrg1-3 z26 mimicthemimic therbb3b3b pigment pattern phenotype.

To investigate the impact of this modification on membrane binding, we generated mutants mimicking the phosphorylated (S94E/T100E) and the unphosphorylated (S94A/T100A) state of the protein.

Arabidopsis seedlings treated with TSA and histone deacetylase mutants mimic the phenotypes of hsi2-2/hsl1double mutant seedlings [ 12, 13], indicating that HSI2- and HSL1-mediated repression of the embryonic program could involve histone deacetylation.