Moreover, in mechanically protected anatomic niches like the anterior nasal cavity and the buccal mucosa of the oral cavity of mutant mice, well-developed fragments of normal appearing non-keratinizing squamous epithelium were present.
Jag2 mutant mice are well known to have syndactylism [24], [25].
Negligible levels of freezing were observed during the pre-tone period in control and mutant mice as well as RU-486-treated Gγ7-mCrePR mice (RU-486 control).
We found that Per2Brdm1 mutant mice as well as mice lacking Cry2−/− displayed significantly increased bone volume at 12 weeks of age, when bone turnover is high.
Representative ERG waveforms from dark and light kept mutant mice as well as from a WT are shown in Fig. 2B.
Since no relationship has been established between the hox genes and Rho proteins to date, it would be interesting to analyze whether RhoE is altered in the HoxD mutant mice, as well as in the EphA4 −/− mice.
Vegfc mutant mice as well as zebrafish lack a lymphatic system [ 11, 12].
This paper describes the phenotypic characterization of these mutant mice, as well as mapping, identification and characterization of the mutant gene.
We examined carefully the prostate of 1-week-old and 4-week-old mutant mice as well, but no histological changes were detected (data not shown).
Exons of candidate genes were sequenced for wild-type and mutant mice, as well as parental controls, at the McGill University and Génome Québec Innovation Centre.
Our model reproduces the phenotype of both wildtype and relevant mutant mice, as well as the results of most culture conditions described in the literature.
