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Abate-Shen showed that prostate tumors from low-testosterone mutant mice shared a similar gene expression profile to androgen-independent prostate tumors [ 50].
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Therefore, we conclude that the mPer2 mutant mice share the breakdown of the universal organization of resting periods with human depression patients.
We have found that circadian gene-mutant mice share common aging and cancer-prone phenotypes although these symptoms may be more evident at different times during lifespan or under different physiological conditions in different mouse models.
Even though df/df mice share several characteristics with GHRKO mice, these two groups of mutant mice exhibit traits exclusive to their genotypes.
Unfortunately, the genetic history of mutant mice is often ambiguous when mice are shared between institutions (Sellers et al. 2012).
The lens cataract and myopathic muscle in mutant mice and humans with the αB-crystallin R120G mutation shared common pathological features and molecular mechanisms.
Using the postsynaptic scaffolding protein Shank3 as an example, Dr. Feng will discuss: (1) circuitry mechanisms of repetitive behaviors in mouse models of ASD; (2) reversibility of synaptic, circuitry and behavioral abnormalities in adult mouse models of ASD; (3) shared and distinct synaptic and behavioral phenotypes in two lines of Shank3 mutant mice linked to ASD and schizophrenia.
Mice expressing a truncated ameloblastin (lacking exons 5 and 6), share similar histopathological features to the Y64H amelogenin mutant mice reported here (8, 31).
You've got some normal mice and some mutant mice.
B.Cha. provided Gnat1rd17Gnat2cpfl3 double mutant mice.
Generation and characterization of dickkopf3 mutant mice.
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