Sentence examples for mutant mice related from inspiring English sources

These observations suggest that increased USVs may be a common feature in mutant mice related to autism.

This apparent loss of immune self-tolerance in mutant mice may relate to an inability to functionally inactivate autoreactive lymphocytes, since Itch-/ T cells have been found resistant to the induction of anergy by low doses of ionomycin [ 78].

As mice and humans differ in their major CoQ isoform (CoQ9 and CoQ10, respectively), it remains possible that the failure of high-dose CoQ10 supplementation to prevent or cause sustained improvement of disease manifestations in Pdss2 mutant mice may relate to the minor CoQ10 isoform we supplied.

As expected, survival of mutant mice was directly related to the extent of PT treatment (Fig. 3B).

We demonstrate that impaired autophagy underlies neurodegeneration in these mutant mice and is likely to contribute to related human disorders.

Such a discovery opened the possibility to create numberless models of human diseases, and related mutant mouse strains by manipulating the genome in ESc.

Together these data uncover a distinct behavioral phenotype according to which the NOS2 mutant mice are more susceptible to stress, a trait likely to be related to an increased basal NOS activity in their CNS.

In addition, mutant mice spontaneously underwent late onset progressive hearing loss and vestibular dysfunction related to substantial hair cell death.

In this case the "free-floating mitochondria" were interpreted as a result of a blood brain barrier breakdown related to a basement membrane defect in Sod1 mutant mice [ 25].

The downregulation of CDKN1B found in prostate lesions in Men1 mutant mice suggests the in vivo importance of CDKN1B inactivation in the tumorigenesis related to Men1 inactivation, similar to observations in other mouse Men1 tumour models [ 12, 37- 39].

In order to unravel whether a change in Cry1 light induction is related to the observed high amplitude resetting in our double mutant mice, we generated Rev-Erbα−/−Per1Brdm1Cry1−/− triple mutant animals (Fig. S4).