Sentence examples for mutant mice even from inspiring English sources

Elevated levels of nuclear-localized activated Smads were also detected in skeletal muscle from X-linked muscular dystrophic (mdx) mutant mice, even in the absence of myostatin [20].

For example, our results reveal an unexpected delay in the initiation of puberty and an altered estrous cycle in the mutant mice, even without active stimulus presentation.

We did not observed spontaneous epilepsy in Atp6ap2 CamiceCre/0 mice and mutant mice even had reduced susceptibility to epilepsy induced by PTZ administration.

Quantitative analysis of all brain regions with detectable neuronal Arc expression after visual stimulation showed no differences in characteristics of network-wide Arc responses between control and mutant mice, even in the brain areas with the highest tangle load.

In short, syntactic chains were initiated early in a grooming bout by all mice, but mutant mice were even more likely than wild-type mice to initiate chains during those early portions of a grooming bout, and the mutant advantage was greatest in the laboratory environment (which might be the most stressful environment).

Direct gene therapy to the spinal cord using the same lenti-GDNF construct described in the current study has previously been attempted with no protective effect on lumbar motor neurons in the mutant SOD1 mouse, even though high levels of GDNF secretion was achieved [14].

A systematic examination of pain-related behaviors in BDNF heterozygote mutant mice also indicated that even reduced gene dosage of this important factor can lead to deficits in acute noxious heat sensitivity and reduced pain behaviors, e.g. in the formalin test (MacQueen et al., 2001).

But the mutant mice were still quite startled, even with the warning sound.

Normal metaphyseal zone mineralization was noted even in mutant mice with marked hypertrophic zone underdevelopment.

In the case of crtc3, humans with gain-of-function polymorphisms are at higher risk for obesity, and homozygous ctrc3-deficient mutant mice are resistant to obesity even when fed a high-fat diet (Qi et al. 2009; Song et al. 2010).

It should be however noted that Erg loss-of-function does not induce an overt vascular phenotype in homozygous mutant mice, as blood vessels seem normal, even though the primitive vascular network shows dilated vessels [55].