Sentence examples for mutant mice delayed from inspiring English sources

In baffled mutant mice, delayed, disorganized and overfasciculated CT neurons are observed in the IC.

Local mIGF1 expression significantly lengthened the lifespan of SRF mutant mice, delayed the process leading to DCM and improved cardiac functions.

Interestingly, the ablation of cyclophilin D in SOD1 mutant mice delays disease onset, and CsA treatment is beneficial [172,173].

These findings led us to propose that hair growth cycling in Bmal1 mutant mice is delayed due to upregulation of p21, leading to slowed G1-S cell cycle progression in progenitor cells of the secondary hair germ.

However, cell type selective excision of mutant SOD1 from motoneurons of transgenic mice delayed disease onset, while excision of mutant SOD1 from microglia slowed disease progression (Boillee et al. 2006b).

The general MMP inhibitor GM6001 causes delayed cartilage remodeling and delayed bone formation during fracture repair, whereas Mmp2-null mutant mice only exhibit delayed bone remodeling.

Notably, mutant mice display a delay in wound healing and developed keratoacanthoma-like lesions with massive keratin deposition around the wound margins (Supplementary Figures S5B and C).

Dyrk1A−/− null mutant mice show growth delay and die during midgestation whereas mice heterozygous for Dyrk1A mutation (Dyrk1A−/+) display a brain size 30% smaller than wild type with a region-specific reduction of neurons (Fotaki et al, 2002; Benavides-Piccione et al, 2005).

Previous reports show that crossing mutant SOD1-Tg mice with dynein heavy chain mutant mice (loa or cra) delays the disease onset and extends survival (34, 35).

Further, we show that osm-3/kif17 mutant mice also exhibit a similarly delayed outer segment development, suggesting a role for osm-3/kif17 in early outer segment development that is conserved across species.

However, CaSR−/− mutant mice die prematurely and exhibit delayed growth, preventing the preparation of synaptosomes from these animals.