Sentence examples for mutant mice data from inspiring English sources
At 24 hours after thioglycollate injection similar numbers of cells were recovered from the peritoneal cavity of control and mutant mice (data not shown).
No gross morphological difference for SM, heart or liver was observed between wild type and Fsp27 mutant mice (data not shown).
However, the proliferation index of colonic epithelial cells in young adult mice was comparable between control and Hnf4α mutant mice (data not shown) and was consistent to what has been reported in the colonic embryonic situation [10].
However, this mechanism is unlikely to cause the ATGL induction in the Tsc1−/− HFD-fed livers since high-fat diet suppressed PPARγ expression in both wild-type and mutant mice (data not shown).
No significant difference was observed in the presence and localization of differentiated intestinal cell lineages (enterocytes, enteroendocrine, goblet cells and Paneth cells) in the FHL2 mutant mice (data not shown).
Notably, analysis of CD8+ SP cells for which the TCR repertoire variability had been reduced by expression of the MHC Class I-restricted H-Y or P14 TCR transgene (tg) [26], [27] inferred an altered TCRαβ selection in the mutant mice (data not shown).
At E12.5, we did not observe defects in the cushions of any of the mutant mice analysed (data not shown), except for Robo1 Robo2 mutants.
Given that mdx mice exhibit similar if not greater levels of muscle degeneration/regeneration than Dysferlin mutant mice, these data suggest that the cholinergic signaling defects in Dysferlin mutant mice are not due to generalized muscle damage or regeneration.
Our preliminary data indicate, however, that combining Ifih1 with Adar1 does not rescue the lethality of the Adar1 mutant mouse embryo (data not shown), suggesting that MDA5 is not the sole mediator of the Adar1 mutant phenotype.
But reviewing audiograms revealed no ABR threshold difference between mutant mice and control mice (data not shown).
Expression of p110α, p110β, and p85 in muscle, liver, and fat was also equivalent in mutant and control mice (data not shown).
