Sentence examples for mutant mice by from inspiring English sources

Wolfe, A. R. et al. Suppression of intestinal tumorigenesis in Apc mutant mice by Musashi-1 deletion.

Mashiko, D. et al. Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.

Here, we created reporter and conditional mutant mice by coinjection of zygotes with Cas9 mRNA and different guide RNAs (sgRNAs) as well as DNA vectors of different sizes.

Furthermore, they created the mutant mice by gene targeting method using mouse 129/Sv embryo-derived stem (ES) cells and performed analysis on a mixed C57BL/6 X129/Sv genetic background13.

Marino, S., Vooijs, M., van Der Gulden, H., Jonkers, J. & Berns, A. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.

Based on recent advances, here we provide experimentally validated, detailed guidelines for generating non-homologous end-joining (NHEJ -mediated mutaNHEJ -mediatedroinjecting TALENs and RGENs into the cytoplasmutanthe pronucleus of one-cell stage micee embyyos.

We checked that the Notch pathway was truly inactivated in the intestine of the double-mutant mice, by showing that efficient recombination of the floxed RBP-J alleles had occurred after tamoxifen injection (figure 5C).

Lens opacities were confirmed in R49Cneo mutant mice by slit lamp analysis.

Clock Δ19 lengthens circadian free-running period by about 1 hr in heterozygous mice, and by about 4 hr in homozygous mutant mice followed by arrhythmicity upon exposure to constant darkness (DD).

ManNAc treatment appeared to ameliorate the hyposialylation status of mutant mice, indicated by a lectin histochemistry pattern similar to that of wild-type mice, with improved sialylation of both nephrin and podocalyxin, as well as reduced albuminuria compared with untreated mutant mice.

Most mice have 13 pairs of ribs, but a few strains of mutant mice bred by Mallo and colleagues have 24 pairs.