Following inoculation with PsmES4326, the mutant lines supported similar levels of bacterial growth as wild-type plants.
The composition of the fad7 fad8 mutant line supports this contention, in which the mol% of 18 2 is almost 2-fold higher than that of wild-type membranes and this line exhibited the best growth at elevated temperature.
This different GFP expression level between WT and mutants was consistent in multiple transgenic lines; supporting that it reflected the actual effect of cry1 and HFR1, but was not due to the insertion difference.
FGFR3 mutant cell lines had significantly fewer UPD events and overall size of the genome affected by UPD than wild type lines, supporting that UPD associates with aggressiveness (Additional file 2: Figure S6).
Additionally, although STF-31 was initially identified for its selective inhibition of a VHL mutant renal cell carcinoma (RCC) cell line over an isogenic line overexpressing VHL, in our collection of 20 RCC cell lines STF-31 shows somewhat greater inhibition of VHL wild-type lines (Supporting Figure 2).
Additional functional annotation such as source (publication, website, etc...), criteria used to determine the function, CA comments, putative subcellular localization, primer sequences, accession numbers of supporting evidence, or mutant lines can also be entered.
Finally, to complete the pharmacological characterization of the mutant mGlu1 receptors, we examined the effect of an mGlu1 NAM in high efficacy (K653N) and moderate efficacy (A683E) mutantmutant lines and compared it then to WT mGlu1 (Supporting Information Figure 1).
The expression data supported the role of AtMMS21 during gametophyte development inferred from the mms21-1 mutant lines.
More than 90 mutant lines have been induced for this locus from two-rowed barley (Lundqvist et al., 1997), which supports the hypothesis that six-rowed barley was derived from two-rowed barley by mutation.
Jeng et al. (2012) discovered mutant lines that have higher Fe or Zn concentrations in polished seeds by searching among NaN3-induced mutant lines (Oryza sativa cv. IR64).
