Your English writing platform
Discover LudwigSuggestions(2)
Exact(1)
We observed that mutant larvae express decreased levels of myc mRNA and pre-mRNA.
Similar(59)
By contrast, 92% of gnbp3 mutant larvae expressed Drs following the same immune challenge (Fig. 3C).
Significantly, atg6 mutant larvae expressing activated Trc displayed decreased formation of blood cell mass in contrast to control atg6 mutant animals, suggesting Trc can function downstream of Atg6.
Wild-type and kif5aa mutant larvae expressing genetically encoded calcium indicators (GCaMPs) in different subsets of neurons of the visual system were confocally imaged in the tectum contralaterally to the stimulated eye (dashed box inset).
Consistent with the results reported by Pickart et al., apoc2 mutant larvae show a slightly delayed yolk consumption (Fig. 3A-G) and the mutant larvae are smaller than WT larvae.
These results complement our electrophysiological observations and indicate that the restoration of synaptic transmission by Rab11 overexpression recovers the disrupted behavioural readouts of larvae expressing mutant htt.
Larvae expressing mutant DNM2 DNM2-S619LL) had structural abnormalities in the triad, the skeletal muscle substructure that represents the intersection of the T-tubule and terminal sarcoplasmic reticulum.
One possible explanation for the anomalies described above occurring at the NMJ in zebrafish expressing mutant TDP-43 is reduced calcium ion entry in the presynaptic terminal during the action potential; these defects were completely prevented in larvae expressing mutant human TARDBP treated with L-type calcium channel agonists (Armstrong and Drapeau, 2013a).
Third instar larvae expressing these mutant proteins under control of the hsp70 promoter were heat shocked and salivary glands were stained with antibodies to Drosophila Lamin C and lamin Dm0.
Interestingly, relaxed larvae expressing β1aAAA mutant revealed movement profiles similar to relaxed larvae expressing WT β1a, with double-peaks representing larval muscle contraction and relaxation [17].
Larvae expressing wild-type Lamin C crawled to zone 3, whereas the larvae expressing the mutant forms remained in zone 1.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com