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Interestingly, before dying, the fga mutant larvae exhibit defects in the process of gas filling of the respiratory (tracheal) system, a process that normally occurs by the end of embryogenesis [20].
Here, we show that zebrafish quetschkommode (que) mutant larvae exhibit a progressive locomotor defect that culminates in unusual nose-to-tail compressions and an inability to swim.
These results are consistent with the observation that Slbp15 mutant larvae exhibit a developmental delay before the onset of lethality.
Notably, Pex1 mutant larvae exhibit abnormalities that are analogous to those exhibited by Zellweger syndrome patients, including developmental delay, poor feeding, severe structural abnormalities in the peripheral and central nervous systems, and early death.
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Knockout mutations in zc4h2 were created in zebrafish and homozygous mutant larvae exhibited abnormal swimming, increased twitching, defective eye movement and pectoral fin contractures.
Homozygous mutant fish were viable beyond embryogenesis, and all mutant larvae exhibited abnormal flexion of the pectoral fins and abnormally positioned eyes when compared with wild-type siblings (Fig. 4A D).
The present study reports on a Bicyclus anynana (Lepidoptera: Nymphalidae) dark larvae single locus mutation, in which larvae exhibit a darker cuticle relative to wild type.
In gho mutant larvae traces of shallow taenidia can be distinguished at the ultrastructural level (Figure 6F).
kcnh4a -/- larvae exhibit increased locomotor activity compared with kcnh4a +/- and kcnh4a / under LD conditions.
For example, third instar Drosophila larvae exhibit peristaltic patterns of motion for locomotor behavior.
Drosophila larvae exhibit stereotypical crawling behaviour when placed upon an agarose surface (31).
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