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The asl3 mutant was a lethal mutant isolated from a 60Co-irradiated population of japonica variety Jiahua1 (WT).
Here, we report characterization of a mutant isolated from a genetic screen in Arabidopsis thauana designed to identify plants defective in degradation of an Aux/IAA fusion protein, Aux/IAA1-luciferase (IAA1-LUG).
They used a mutant (isolated from a previous trial) that was capable of metabolizing a given resource and compared the reproductive success of that mutant strain to that of a "wild-type" strain.
However, imatinib did not stimulate the nuclear import of the Y253E mutant (Figure 5B), which is consistent with the fact that BCR-ABLY253H was an imatinib-resistant mutant isolated from drug-resistant CML cells [35].
Since 57-4 was a natural doubled haploid mutant isolated from Pima S-1, both are natural isogenic lines.
The asl1 mutant is an albino, seedling-lethal mutant isolated from japonica rice Jiahua1 irradiated with Co gamma rays.
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However, a recent study of siderophore mutants isolated from CF patients found that the majority carried mutations in the regulatory gene pvdS (Andersen et al., 2015).
Here we describe auditory/vestibular mutants isolated from forward genetic screens in zebrafish with lesions in the adaptor protein 1 beta subunit 1 (ap1b1) gene.
This may explain the relative scarcity of the toxic mutants isolated from the screen.
Regarding mutants isolated from environmental samples, only one with the zanamivir- related R152K mutation was found, dating from 2004 (Table 4 and Table S1).
For the complementation studies 10 Fos-R mutants isolated from 10 different non-treated mouse lungs inoculated with the wild type strain, were complemented with the plasmid pBBR-glpT, as previously described [37].
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