Sentence examples for mutant is thought from inspiring English sources

Because the NMD pathway is an mRNA surveillance mechanism, seed-size alteration in the lba1 mutant is thought to be due to altered posttranscriptional regulation of NMD-targeted gene(s) [82].

The activated Pol V assembled with the mutant is thought to have an interesting hybrid ATP hydrolysis site where one or another surface of the other proteins may provide a residue compensating for the loss of the charge in the RecA.

Originally, the npr1 mutant was thought to be only deficient in SA-mediated defense.

Interestingly, both mpk-1 mutant worms and germline deficient glp-1 mutants exhibit elevated baseline stress resistance when compared with wild type control animals., The stress resistance of glp-1 mutants is thought to reflect the general stress resistance that can be caused by a complete ablation of the reproductive germline.

The appearance of ALM posterior neurites, seen in ptrn-1 mutants, is thought to be a neuron polarity defect (Hilliard and Bargmann, 2006; Kirszenblat et al., 2013; Prasad and Clark, 2006), and the cell body puncta seen in animals expressing PTRN-1 mcherry PTRN-1 mcherrybule organizing centers necessary for polarized neurite outgrowth.

The supernumerary incisors in Wise mutants are thought to form as a result of the successive development of the rudimentary tooth germs, since apoptosis is reduced in the incisor region [41].

Most nonsense (insertion/deletion) mutants are thought to result in unstable transcripts and in little or no mutant protein production [ 6].

Moreover, certain p53 mutants are thought to acquire new functional properties that can influence gene expression levels in a manner that is unaffected by wild type p53.

These high TK activity mutants are thought to simulate the conformational changes caused by activation segment phosphorylation, resulting in protein ligand-independent constitutive activation.

SHH pathway mutations are directly associated with midline defects whereas TGF β pathway mutants are thought to act upstream of SHH, affecting SHH expression and/or activity in the prechordal plate (Rohr et al., 2001).

Previously, the mechanisms responsible for the longevity of IIS mutants were thought to be different from those underlying the longevity of TOR mutants or animals subjected to DR. Mutation of let- 363 (the worm TOR orthologue) together with daf- 2 does not have an additive effect on lifespan (Vellai et al. 2003) suggesting that the two pathways act by common mechanisms.