Sentence examples for mutant is required from inspiring English sources

The result shows that a higher amount of mutant is required to reach 50% maximal response.

As the use of this mutant is crucial for major conclusions of your work, comprehensive characterization of this mutant is required before further consideration of your submission.

Our data also indicate that the residual phosphatase activity associated with the LS SHP2 mutant is required for enhanced ERK1/2 activation.

Our data with a catalytically dead double mutant Y279C/C459S provide further evidence that the residual phosphatase activity associated with the LS SHP2 mutant is required for enhanced ERK1/2 activation.

However, to facilitate a rational drug discovery approach, a greater understanding of the GCH1 : GFRP complex and the potential limitations of the current crystal structures (which used an N-terminal truncation mutant) is required.

For common point mutations, a typical threshold of 80 90% mutant is required to manifest as disease at the cellular level, and tissue levels correlate loosely with the severity of the clinical phenotype.

Inoculation with 11,136 CFU of the mutant was required to cause skin ruffling and death of some mice, which is a lower dose than that required for clinical symptoms by the IN route.

An IP challenge in HSB with 1,000 times the lethal WT K288 dose (3×108 CFU) of the ΔsimA mutant was required to generate comparable mortality to WT K288 (data not shown).

For blocking the CDP-Etn branch of the Kennedy pathway efficiently a cki1Δdpl1Δeki1Δ triple mutant was required.

Although Tor signaling normally inhibits autophagy, the high level of phosphorylated S6K maintained by the mutant was required for precocious starvation-induced autophagy.

DOI: http://dx.doi.org/10.7554/eLife.05795.004 An early in vitro MCM loading assay utilizing purified proteins together with crude extracts reported that Cdc6 ATP hydrolysis (using the Cdc6-E224G mutant) was required for MCM loading (Randell et al., 2006).