Sentence examples for mutant is primarily from inspiring English sources

The quaternary structures for the S57K/N59E/E73K/S102D and S57K/N59E/E73K/S102D/H74K/D78P/D80E/D87G mutants of c-NADP-ME are tetrameric, whereas the K57S/E59N/K73E/D102S m-NAD(P -ME quadruP -MEutant is primarily monomeric with some dimer formation.

Therefore, the markedly elevated serum with only moderately higher hepatic bile acid levels in the double mutant is primarily due to the decreased hepatic uptake.

Furthermore, although there is no conventionally significant difference, the increase in bulk IFN-γ responses observed with the B15R deletion mutant is primarily the result of an increased number of these double-positive cells, rather than of the IFN-γ single-positive or the IFN-γ, TNF-α and IL-2 triple-positive cells that account for the remainder of the CD8+ T cell response.

We tentatively suggest that the reduced activation efficiency of the CarD-W86F mutant is primarily due to the loss of the minor groove polar interaction with T−12 nt).

Moreover, because attenuation of the mptC mutant is primarily observed in the context of innate immunity, and zebrafish DCs are not detected before 5 7 dpf (Lugo-Villarino et al., 2010; Wittamer et al., 2011), it is unlikely that the observed phenotype results from a disrupted DC-SIGN binding and/or DC modulation.

This conclusion is based on the observation that the low fidelity of I260Q mutant is primarily determined by enhanced efficiency of mismatched incorporation, whereas for most low fidelity DNA polymerase variants, reduced fidelity correlates with low efficiency of correct dNTP incorporation (41).

The OsISA1 gene sequence (Os08g40930) of Hwacheong and sug-h mutant was primarily compared, because previous studies reported that OsISA1 affected the sugary phenotype in sug-1 rice (Kubo et al. 1999; Nakamura et al. 1992; Nakamura et al. 1996).

We concluded that the hydrophobicity and pathogenicity defects in the ΔpdeH mutant were primarily due to the low level of MPG1 expression, and it is likely that the expression level of MPG1 must remain at 150% of wild-type or more to maintain the surface hydrophobicity.

Although this does not exclude the possibility that M1 protein regulation might also occur at other levels, it is clear that the reduction of M1 protein in the dltA mutant was primarily due to a decrease in the level of emm1 mRNA transcript.

The M1 protein deficit in 5448ΔdltA was largely reversed by complementation with pdltA (Fig. 2), suggesting that the reduction of cell wall M1 protein in the mutant was primarily attributable to the loss of dltA and not to a secondary mutation.

The shorter root meristem in brassinosteroid mutants is primarily due to shortened cell length, whereas the shorter meristem in exocyst mutants is due to fewer cells.