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To generate a smooth landscape, the newly created mutant is assigned a mutant neighbourhood which is identical to that of the ancestral strain, leading to a landscape with only a single global optimum.
For the smooth landscape, each newly created mutant is assigned a mutant neighborhood that is identical to that of the ancestral strain.
At the other extreme, for a completely rugged landscape, every new mutant is assigned an entirely new L-mutant neighborhood with values for the fitness effect of each new mutation re-sampled from p(s).
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The other seven up-regulated proteins in the DsRNA- Xoo3 mutant were assigned to various metabolic functions, including glutathione metabolism, fatty acid metabolism, lipopolysaccharide, and sucrose metabolism.
In line with this theory, a large proportion of genes which are differentially expressed between the wild type and mutant were assigned to functional categories related to defence and environmental interactions.
Gene Ontology (GO) terms for all mutants were assigned and compared between LT+ and LT− groups (Fig. 2; Table S1 shows all GO assignments), to look for enrichment of particular functional categories.
The mutants were assigned to two main classes: those retaining pre-40S particles in the nucleoplasm, which could be genuine mutants in the export pathway, like Ins3, Ins5, Ins13, Ins17, and Δbud23; and mutants affected in early, nucleolar steps in ribosome biogenesis, such as Ins11, nhp2ins9, utp15ins15 and Δslx9.
The DNA from each recombinant progeny exhibiting the mutant phenotype is assigned to a specific well in a 96-well plate and remains the same for each individual reaction.
However, in dpy-28 mutants, this phenomenon is assigned to elevated numbers of meiotic DSBs, rather than altered DSB repair (Mets and Meyer 2009).
Gene function is assigned based on phenotypic evaluation of the mutant individuals.
Every clone is assigned a 1-step neighborhood of L mutants that can be reached by a single mutation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com