Sentence examples for mutant induced a from inspiring English sources

Infection with the pilY1− mutant induced a strong acute inflammatory response in murine airways, but no mortality (data not shown).

The hNGFR100E mutant induced a significantly lower activation of Erks, with respect to hNGF (Fig. 1E,H), which is not due to a different time course (data not shown).

The ΔSPI-1 mutant induced a high, dose-dependent M1 response but a low M2 response in infected macrophages.

Because the G190S mutant induced a large positive shift of activation voltage dependence, we tested whether ACTZ is able to contrast G190S defect.

Abolishing Myo1c function by RNA interference or overexpressing a dominant-negative mutant induced a collapse of raft-enriched recycling tubules and lipid rafts accumulated in the recycling compartment causing a dramatic loss of raft markers from the cell surface.

By extending the infection time to 11 h, the tir mutant induced a rapid loss in barrier function after the lag, which occurred at a rate over 6 times faster (P < 0.0001) than the decrease with WT EPEC (Fig. 1C), while a TER decrease was not observed with the espA mutant over a similar 11 h infection period (Fig. 1C).

The single mutations induced a leukemia similar to wild type when transplanted into mice, however the double mutant induced an undetermined disease with recipients surviving twice as long as wild type recipient mice [25].

In the context of inactive LKB1, the overexpression of EIF2A and the EIF2A-S51D isoform led to a protective effect, while the alanine mutant induced an increase of cell toxicity (Fig.  6c).

We hypothesize that the mutant induces a repressor that acts against the ABA pathway or downregulates an inducer of the same pathway.

Altogether, these results highlight the fact that the reduced QC size in the mutant induces a decrease in cell division and premature cell differentiation in the rice RAM.

Indeed, S620T mutant abolishes inactivation [25], [43] while S631A mutant induces a depolarizing shift in the steady-state inactivation relation [40].