Sentence examples for mutant in zebrafish from inspiring English sources

Exact(12)

In this study, we analyzed the role of myosin in myofibril assembly and compared it with that of hsp90α1 mutant in zebrafish embryos.

Previous studies on the kto/med12 mutant in zebrafish showed multiple defects in tissue development in the neural crest, brain, kidney and elsewhere [6], [7], [8], [9].

Analysis of the trilobite mutant in zebrafish (the stbm ortholog in fish) showed that the first of these events is not regulated by stbm, whereas the second is ([29]).

Results Using a forward genetic screen for craniofacial mutants, the authors identified a gata3 mutant in zebrafish.

Studies of a sod1 mutant in zebrafish opened the possibility of screening small molecules for recovery from the phenotype.

Interestingly, the sox9a/b mutant in zebrafish displays a truncated notochord, supporting the notion of a function of sox9 in chordocytes [ 37].

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This paper is centered on developing new techniques for screening genetic mutants in zebrafish, especially those affecting development of motility in this interesting vertebrate animal.

Taken together, our results suggest that TALEN technology provides a robust alternative to CoDA ZFNs for inducing targeted gene-inactivation in zebrafish, making it a preferred technology for creating targeted knockout mutants in zebrafish.

The lack of early phenotype in cfl1 insertion mutants in zebrafish [30] is puzzling and contradictory to the necessity of cofilin as demonstrated in Xenopus embryos [27].

Although we found upregulation of Δ113p53 transcript in L11-deficient embryos (data not shown), it was consistent with the data from other RP mutants [38] and ribosome-associated protein mutants in zebrafish [39] which reported upregulation of Δ113p53 isoform.

In addition, ILK-null mutants in zebrafish are rescued by wild-type, kinase-active ILK, but not by ILK containing mutations within the kinase domain [13], and kinase-deficient mutants of ILK have been identified in the myocardium of patients with dilated cardiomyopathy [43].

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