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He's a movie star because he played a mutant in three X-Men films.
As shown in Fig. 3A, no tested metformin concentration significantly increased the median lifespan of either aak-2 mutant (in three repeated trials for each strain; Table S1E).
The Tex19.1-null mouse mutant phenocopies the Ubr2-deficient mutant in three aspects: heterogeneity of spermatogenic defects, meiotic chromosomal asynapsis, and embryonic lethality preferentially affecting females.
Another histone, H2B is mutated in seven out of 377 glioblastoma multiform patients, resulting in a G53D mutant in three cases (in HIST1H2BE, HIST1H2BL and HIST1H2BF).
We found four genes, out of the 22 commonly mutant genes (Group I), also had non-silent mutations in at least three other TCC patients, including CFTR (mutant in seven patients), NIPBL (mutant in five patients), ASTN1 (mutant in four patients) and DHX57 (mutant in three patients), which were all novel findings of this study.
The putative SMs were filtered based on the following criteria: (1) homozygous normal in all normal cells (at least read-covered in six normal cells); (2) the homozygous genotypes in normal cells were consistent in normal tissue; (3) at least mutant in three cancer cells among a total of 44 qualified cancer cells.
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Jackman, who has starred as the adamantium-clawed mutant in six films stretching back to 2000's X-Men, said he would be unlikely to play the part beyond next May's X-Men: Days of Future Past.
Here, we report the crystal structures of Mac-1 and its catalytically inactive C94A mutant in two different crystal forms.
One mutant in tw, tw1, has been reported.
Analysis of the virulence of the Δafoch1 mutant in two murine models of infection revealed no attenuation.
The wild-type strain grew from Klett 70 to Klett 200 in one hour and the ecsA::intron mutant in two hours, indicating that overexpression of a secretory protein causes severe stress and growth inhibition in the mutant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com