Sentence examples for mutant in conjunction from inspiring English sources

A possible alternative is to modify the dimerizable partners fused to the Cre moieties themselves and use a mutated FKBP12 only, such as the F36V mutant, in conjunction with homodimerizer drugs that do not interfere with endogenous FKBP12 but have good pharmacokinetic characteristics [47] [49].

Matsuzaki et al. [ 19] demonstrated that a tyrosine-sulphated form of CLEL8 (restoredstoRAM RAmaintenancece of a tyrosine sulphotransferase mutant in conjunction with PSK and PSY1.

The reported increases in SA levels and the gamut of phytohormone responsive genes and redox transmitters that are altered in the Atnudt7-1 mutant in conjunction with the observed changes in NAD+, NADH, GSH and ascorbate, suggests novel interconnections between redox signaling, antioxidative systems and phytohormone-mediated oxidative cell death pathways [ 31] (Fig. 10).

It was recently shown that col- 26 in N. crassa also functions in nutrient signaling and that a Δ col- 26 mutant, in conjunction with a deletion of the carbon catabolite repressor, cre- 1, suppresses the inability of a Δ vib- 1 (a NDT80-like transcription factor) mutant to utilize cellulose [ 27].

The mild growth defect of the OmpU mutants in conjunction with the low prevalence of ICP2 (Seed et al., 2011) may explain why the ICP2-resistant ompU variants do not become fixed in the population.

Careful comparison and staging of the developmental arrests caused by the different mutants in conjunction with expression analyses of specific markers (such as the genes involved in wnt, FGF and Eda signaling) will be required for the development of a cohesive model of the genetic interactions among these pathways.

Previously we engineered a N346A/C348A mutant of PylRS (PylRS N346A/C348A)) and demonstrated that this mutant enzyme in conjunction with tRNA CUA Pyl was able to incorporate a wide range of tyrosine and phenylalanine derivatives into proteins in response to the amber codon in E. coli.

The creation of a R349P desmin knock-in mouse model expressing untagged mutant desmin in conjunction with the generation of a R349P mutant-specific antibody allowed us to analyze these central issues in relation to the clinical, hemodynamic, morphological, and biomechanical aspects of desminopathies.

This conclusion was based on the toxic properties of the mutant protein in conjunction with its retention of activity.

We found that mutant TP53 in conjunction with active estrogen receptor (ER) signalling significantly influence survival.

HEK293T were transfected with expression constructs for wildtype Taspase1::Flag and the dnTASP1::Flag mutant variant in conjunction with an AF4 MLL expression plasmid.