Sentence examples for mutant has shown from inspiring English sources

For example, the TOP3 and RAD1 double mutant has shown extreme synergistic growth defects in a previous study [ 34].

The Surv-T34A mutant has shown promise in initiating the mitochondrial apoptotic pathway (Mesri et al, 2001) and if also detected extracellularly could provide a form of survivin suitable for therapeutic manipulation.

The most abundant polysaccharide in the A. fumigatus cell wall is α(1,3 glucan and among the three α(1,3 glucan synthases identified in the fungus genome, only Δ ags3 mutant has shown virulence changes (hypervirulence) in an experimental mouse model of aspergillosis [ 27].

Analysis of the Cbx1 null mutant has shown that the Cbx1 gene product, HP1β, is required for proper development of the brain, with Cbx1-/ neurospheres cultured in vitro showing a dramatic genomic instability that is indicative of a defect in centromere function [ 8].

Previous studies using a F. novicida mglA mutant have shown that lack of MglA results in increased resistance to H2O2 [39].

In this work, detailed phenotypic analyses of a chs2Δ chs8Δ mutant have shown that C. albicans class I chitin synthases promote cell integrity during early polarized growth in yeast and hyphal cells.

Analysis of Cerl−/− Lefty1−/− compound mutants has shown that the AVE does this via the inhibition of Nodal signalling [22].

The characterization of individual bri1 mutants has shown that both the extracellular and cytoplasmic domains of BRI1 are important to its proper functioning.

Analysis of developmental mutants has shown that ovule morphogenesis relies on tightly regulated genetic interactions that can serve as a model for developmental regulation.

Interestingly, a phenotypic analysis of the znuK and znuL mutants has shown that these genes are essential for growth under zinc starvation, suggesting that C. crescentus uses these TonB-dependent outer membrane transporters as key zinc scavenging systems.

Similarly, the creation of UDP-GlcNAc pyrophosphorylase (TbUAP) and glucosamine 6-phosphate N-acetyltransferase (TbGNA1) conditional null mutants has shown that UDP-GlcNAc is also essential for bloodstream form T. brucei (Marino et al. 2011; Stokes et al. 2008).