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This would indicate that YAP, even the transgenicly expressed YAP is under inhibition by the Hippo pathway in intestinal epithelium, so that the Hippo pathway hypo-responsive S127A YAP mutant has different function from the wild-type protein.
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Since the binding pockets of mutants have different amino acids available, the binding properties of compounds may differ.
The two low level resistant mutants had different molecular mechanisms.
The three low-Cd mutants have different mutation sites in OsNRAMP5.
A variety of mutants having different colony characteristics, morphology and soluble pigmentation were generated from Fusarium fujikuroi by exposure to UV radiation.
Despite the existence of this core pathway, its mutants have different effects on miRNA abundance and miRNA target abundance.
It has been reported that antisense TM29 (a SEPALLATA homolog) tomato mutants also exhibits ectopic shoot growth from fruit but these mutants have different flower morphology [27].
As it was expected from previous studies an expression of these two double mutants had different impact on cell morphology.
As previously described [ 9], we found that the three mutants have different sensitivities for Gleevec with PDGFRα-D842V being least sensitive to the treatment and the V561D mutant being most sensitive.
Here we show that the rga28 and gai-t6 single mutants have different seed germination phenotypes, suggesting (at least partially) distinct functions for RGA and GAI in this developmental process.
thyA- deo- double mutants had different thymine/thymidine growth requirements; thyA- 20 μg/ml thymine, thyA- deoA- 20 μg/ml thymidine, thyA- deoC- 2 μg/ml thymine, thyA- deoR- 50 μg/ml thymine [ 35, 36] For viability experiments and RNA sampling, the cultures were handled as follows.
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