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The K464A mutant has comparable activity to wild type, consistent with K30 being the critical residue for sumoylation.
We note that the TRIP13W221A single mutant has comparable activity to fully-stimulated TRIP13, strongly supporting the notion that it can form active hexamers.
This mutant has comparable growth rates to its parental strain, but produces up to 40% less cell wall disaccharide tripeptide owing to a defect in the slt-encoded lytic transglycosylase.
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Each sport has comparable stories to tell.
All engineered mutants had comparable ATPase activity to the corresponding WT protein.
Figure 3 shows that at the stage of four days after egg deposition (AED), wild type and dRecQ4 mutants have comparable BrdU incorporation likely reflecting maternal contributions of dRecQ4 protein in the mutants.
These two mutants had comparable cell-surface distribution as that of KL WT.
wox14 strongly enhanced wox4, such that wox4 wox14 mutants had comparable cell division defects to those observed in pxy wox4 double mutants (Figs 6, 7).
The wild-type (146−231) has the most favorable, lowest interaction energy consistent with previous structural analysis, whereas the Q155N and E159D mutants have comparable unfavorable free energies.
Notably, despite the considerable resistance of the P10P8 and P14P12 α1-antitrypsin variants to polymerization, these mutants had comparable activation energies to the ATC232S control, indicating their effects are manifested during the unimolecular activation phase rather than the multimolecular association phase.
Although the choice of a relA spoT background may influence the growth of the cells in media shift experiments, there is evidence that relA spoT mutants have comparable growth rates to relA+ spoT+ and that the mutations do not influence F plasmid maintenance (Winkler et al. 1979).
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