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The N175H mutant has a broad optimal temperature range from 50 to 65 °C.
In both cases, the L325A/D328A mutant has a higher effect on the demethylase activities of KDM5B.
The unifoliata mutant has a limited growth potential relative to wild-type cochleata, afila and insecatus have extended potentials.
Y. enterocolitica pspC mutant has a severe virulence defect in animal [9], [25].
The Y302F mutant has a tendency to slightly higher surface expression than WT (0.057±0.007, n = 5).
The Phe114Pro mutant has a lower reduction potential.
The R53E mutant has a small effect on RNA-binding, while the R61E mutant has a strong 18-fold effect.
This mutant has a reduced activity on both the p21 and the p53 promoter [ 52].
The Thr157Ala mutant has a very high affinity for bicarbonate (Ka = 0.57 mM).
The "LF" mutant has a milder impact on AnkB's binding to AS or Nav1.2.
This suggests that the mutant has a lower capacity for increasing the de-epoxidation rate.
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