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(D ) Gene ontology (GO) analysis of upregulated transcripts in set1 and clr3 mutant gene expression microarrays.
It indicates that the mutant gene expression and its interaction with mediator molecules during development are critical factors for the SCA1 pathology.
Previous analysis comparing homeotic mutant gene expression relative to wild type revealed significant overlap.
The reported FC is an average of the four replicate mutant gene expression profiles versus the average of all WTs.
To focus on likely direct target genes we intersected the core binding intervals with the mutant gene expression data.
Interestingly, the authors identified a large population of lung tumours with no detectable genetic mutations in LKB1 but exhibiting a LKB1 mutant gene expression profile.
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In selected double mutants gene expression was tested after two hours O3 treatment.
Between the two mutants, gene expression of Cu/Zn SODs transcripts was markedly higher in sodPv 2 mutant.
In a case of relA/spoT mutant, phaD gene expression was independent on the used conditions.
As well as analyses of mutant phenotype, gene expression patterns can provide insight into gene function.
Genes within the mutant EGFR gene expression signature encode proteins with a diverse set of cellular functions.
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