Sentence examples for mutant frequency observed from inspiring English sources

Perhaps there are other SOS induced proteins that might explain the elevated mutant frequency observed exclusively upon NFZ treatment.

Indeed, neither in cortex nor in the remainder of the brain was a statistically significant increase in lacZ mutant frequency observed (although there was a tendency for the mutant frequency at the oldest age to be higher than at younger ages).

The determined fitness values match the HIV mutant frequencies observed within patients and can explain the observed mutation pathway.

A good correlation of mutant frequency was observed between TaqMAMA and the results of clonal sequencing.

For all studied mutagens, a significant and dose-dependent increase of mutant frequency was observed.

Moreover, statistically significant increases in mutant frequency were observed at each BaP dose relative to control (Fig 2; P < 0.01).

Fourfold and twofold increases in mutant frequency were observed for 3-NBA and PhIP exposures, respectively, without the addition of any exogenous metabolic activation.

A dose-dependent increase in mutant frequency was observed in the livers of BaP-treated animals (35.6-fold above control at the highest dose tested; Poisson regression chi-square analysis for BaP concentration effect = 237.95, P < 0.0001).

The value of μ in this spreadsheet was varied until the simulation produced a frequency of mutant cells equal to the median frequency observed experimentally (after a number of virtual generations equal to those required to produce the number of cells that initiate the selection experiment).

When overexpressed, these mutants were much less effective at increasing the binucleation frequency observed in DAPI-stained HFF-hTERT cells (Figure 5B), or the frequency of cytokinesis failure viewed by live-cell DIC microscopy (Figure 5C).

The synergistic reduction in translocation frequency observed when the est2Δ and rad52Δ alleles are combined in double mutants (Table 2), suggests that telomerase deficiency may affect the availability of factors other than Rad52 for DSB-stimulated translocation formation.