Sentence examples for mutant forms that from inspiring English sources

Small-molecule kinase inhibitors have typically been designed to inhibit wild-type kinases rather than the mutant forms that frequently arise in diseases such as cancer.

Her nightmarish ceramics realize the mutant forms that dwell in the dim corners of the imagination, fed through ancient folklore and current pop cultural anxieties alike.

Is the apparent delocalization of MeCP2 mutant forms that have short chromatin residence times also seen at the level of ChIP?

Novel inducible SH-SY5Y and PC12 cell lines expressing human WT and A53T ASYN, as well as two mutant forms that lack the CMA-targeting motif were generated.

Patients expressing mutant forms that retain partial function can be predisposed to seizures.

Mutant forms that are not affected by AT1001 are defined as "non-responsive".

The fusion of human performer, object and music coalesced into a strange, mutant form that was mysterious and equivocal and far more than the sum of its parts.

The efficiency of glycoside prodrug conversion might be improved by design of a prodrug that is more readily activated by human β-glycosidase or by evolution of the enzyme into a mutant form that displays high activity towards these prodrugs.

EhCaBP1ΔEF, a mutant form that does not bind Ca2+ was used as a negative control [9].

The mutant form that is truncated after the R308 residue corresponds to the form of MeCP2 found in the mouse model of RTT generated by Dr. Zoghbi's group [13].

Overexpression of hmutIGFBP3, a mutant form that does not bind IGF, also reduces hypocretin peptide content in brainstem but not in hypothalamus suggesting both IGF dependent and independent effects on hypocretin transmission.