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All the screened subjects were homozygous mutant for one SNP (rs504348) (Table 5).
This technique allows the generation of mosaic clones that are mutant for one gene and expressing another gene under the control of a UAS promoter.
Of course some of them may be mutant for one of the rare alleles that cause surfactant protein deficiency or misfolding, which themselves result in chronic alveolar epithelial endoplasmic reticulum stress syndromes [ 4].
We also observed maternal rescue of morphogenetic and locomotion defects when the parent was homozygous mutant for one Pak, and heterozygous mutant for the other Pak, arguing that both max-2 and pak-1 are maternally rescued.
The LHON fibroblasts were also homoplasmic mutant for one of the three primary mutations.
Much of the understanding concerning the functioning of the circadian clock has come from extensive work done in model organisms mutant for one or several clock genes.
Similar(52)
(D ) MZ oep embryo: maternal-zygotic mutant for one-eyed pinhead (oep), a cell surface protein required for Nodal signaling (Gritsman et al., 1999 ).
Host cells were unresponsive to Nodal because they were maternal-zygotic mutants for one-eyed pinhead (MZ oep ), a cell surface protein required for Nodal signaling.
Expression of puc lacZ is abolished in all DME cells of ush mutants but for one or two which are found at the bend of the germband (and serve as a convenient indicator of the presence of the transgenic construct) (Fig. 4B,B′).
Everyone-and we mean everyone-in the Brotherhood gets an equal vote on how we carry out our dual mission: tirelessly advocating for our mutant brethren on one hand, and introducing the feeble human armies to our stockpile of gassed-up Ford Pintos on the other.
They added molecules to the mutant CRYAB, looking for one that would stabilize their target.
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