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One tumor was mutant for both PIK3CA and BRAF.
To examine this further, we also quantitated embryos double mutant for both NcadΔ14 and spg242.
Consequently, the neurogenesis defects in larvae mutant for both dfmr1 and Ago2 mirror those in dfmr1 null mutants.
Worms that are mutant for both gon-2 and gtl-1 display a growth defect, which is suppressed by supplementation of the food with high Mg2+ [16].
To test whether pnt normally acts downstream of hairy in restriction of the TC fate, we analyzed embryos mutant for both hairy and pnt.
Previous studies of flies mutant for both the PDF and CRY signaling systems concluded that their physiological significance for the clock system lies in their ability to delay the evening activity peak away from a default morning phase [15], [16].
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To assess fine specificity, we measured the binding and kinetics of these mutants for both QL9-L d) and a single amino acid peptide variant of QL9-L dlled QL9-Y5-L(d).
Using ClosTron and allelic exchange mutagenesis, which was demonstrated for the first time in an acetogen, we generated single mutants as well as double mutants for both aor and adhE isoforms to confirm the role of each gene.
As previously mentioned, expression of the Pisd-ps3 pseudogene family is reduced in mutants for both tissues and ages examined.
The activities of all the purified mutants for both trypsin inhibition and blockage of voltage-sensitive K+ channels were measured (Table 2).
We have isolated a few spontaneous drug-resistant mutants for both TAC and SRI-224, which are currently being analyzed in terms of their mycolate profile, cell wall permeability and immunopathogenicity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com