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Mutant flies lacking Gr63a lose both electrophysiological and behavioural responses to CO2.
Therefore, we pre-injected mutant flies lacking PGRP-SA, GNBP1, or PGRP-SD expression with LXB and monitored their survival after septic injury with M. luteus, S. aureus, and E. faecalis.
In agreement with the microarray analysis [35], we confirmed that the induction of PGRP-SB1 expression after E. carotovora or L. monocytogenes injection did not occur in Relish mutant flies lacking a functional Imd pathway (Fig. 1C).
Tbh M18 mutant flies, lacking octopamine, cannot form STM reinforced with 2 M sucrose [ 11].
We will refer to null mutant flies lacking both iPLA2-VIA genes as iPLA2-VIA − / − henceforth.
Insulin-signalling mutant flies lacking the Drosophila insulin-like peptides (DILPs) ilp2, ilp3 and ilp5 were generated as described in Gronke et al., 2010 [ 23].
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This phenomenon apparently occurs because the mutant flies lack a substance called juvenile hormone, which inhibits the flies' ability to enter diapause.
In addition, Dg and Dys (Dystrophin) mutant flies lack climbing ability [24].
We confirmed that mutant flies lacked basal bodies and that the majority of mutant third instar larval brain cells lacked centrioles and centrosomes.
Shak-B mutant flies lack gap junctions at this synapse, which is between the giant fibre (GF) and the tergotrochanteral motor neuron (TTMn), but it still exhibits a long latency response upon GF stimulation.
In loss-of-function dsx mutant XX flies lacking both DsxF and DsxM proteins, basal transcription of the yp genes in the fat body (gonads are not developed) has been reported [31], though in our dsx1 stock such remnant expression was not observed.
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