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In the present work, this tergite could be still smaller in dsx mutant flies expressing the MAo transgene (Figure 3F), whereas in dsx mutant flies expressing the FAo transgene a more female-like development could be observed (Figure 3D).
Flies expressing REMPA::YFP and btv mutant flies expressing NOMPB GFP (btv5P1/Cy GFP; GFP-NOMPB) were obtained from M. Kernan (Stony Brook University, NY, USA).
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To test whether an increase in cAMP levels in the sensory neurons would lead to an increased spiking rate in OR83b knock-out flies (Or83b-/), we generated a mutant fly expressing PACα in the neurons on a OR83b knock-out background.
As mentioned in the above section, "Lethality in tw mutants and flies expressing RNAi for the rt gene," knockdown at 28°C is more efficient than that at 25°C.
(B ) Courtship index comparing miR-124 mutants and flies expressing a miR-124 sponge under dsx-Gal4 control in males lacking one copy of the endogenous miR-124 gene with CS controls.
Hence, we examined the effect of rt or tw on the patterning of muscles by checking the larval body wall muscles in mutants and in flies expressing RNAi for the rt gene.
There was marked accumulation of neuroserpin polymers in flies expressing mutant neuroserpin, particularly the highly polymerogenic H338R and G392E mutants.
Our flies, expressing mutant Htt in the eye, were crossed to candidate RNAi or overexpression (OE) stocks.
Transgenic flies expressing mutant forms of MYOC developed the same fluid discharge phenotype reported previously for flies expressing wt-MYOC [18].
The number of F1 flies was not different between repo-Gal4 positive and negative flies (Table 1), suggesting that embryogenesis of the flies expressing mutant human Htt in glial cells was largely normal.
We also examined mutant discs of transgenic flies expressing a dpn RNAi construct in different domains of the wing blade.
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