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However, when we extended the study to 9 days in DD, doubly mutant flies displayed near 100% arrhythmicity (Figure 2, Table 1).
However, dimm mutant flies displayed a significantly lower fold change in response to Pe for each AMP measured.
These results suggested that azot function was dose sensitive, because heterozygous azot mutant flies displayed delayed elimination of loser cells when compared with azot WT flies.
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Interestingly, scHwUa mutant flies display one or two ectopic bristles (Figure 6C,E) and furthermore a 5-fold increase in sc transcript levels [29].
Null Bug22 mutant flies display cilia-associated phenotypes and nervous system defects.
Likewise, aspm mutant flies display spindle-positioning defects, in addition to increased apoptosis [ 94, 95].
wg mutant flies display abnormal PSD morphology and mislocalized glutamate receptors.
10 13 nwk null mutant flies display synaptic overgrowth at the NMJ and experience temperature sensitive seizures, both phenotypes typical of endocytic mutants.
Drosophila PINK1 (dPINK1) RNAi or dPINK1 mutant flies display a number of phenotypes including altered mitochondrial morphology in both flight muscle and dopaminergic neurons.
In spite of their poor rhythmic behavior in LD and DD, these double mutant flies display reasonably strong rhythmic behavior in LL.
Several long-lived mutant flies have displayed increased resistance to numerous stressors including oxidation, starvation and heat over wild-type flies, indicating a positive correlation between stress resistance and lifespan extension [ 6- 9].
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