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Interestingly, scHwUa mutant flies display one or two ectopic bristles (Figure 6C,E) and furthermore a 5-fold increase in sc transcript levels [29].
In spite of their poor rhythmic behavior in LD and DD, these double mutant flies display reasonably strong rhythmic behavior in LL.
Likewise, aspm mutant flies display spindle-positioning defects, in addition to increased apoptosis [ 94, 95].
Null Bug22 mutant flies display cilia-associated phenotypes and nervous system defects.
wg mutant flies display abnormal PSD morphology and mislocalized glutamate receptors.
Drosophila PINK1 (dPINK1) RNAi or dPINK1 mutant flies display a number of phenotypes including altered mitochondrial morphology in both flight muscle and dopaminergic neurons.
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However, when we extended the study to 9 days in DD, doubly mutant flies displayed near 100% arrhythmicity (Figure 2, Table 1).
However, dimm mutant flies displayed a significantly lower fold change in response to Pe for each AMP measured.
These results suggested that azot function was dose sensitive, because heterozygous azot mutant flies displayed delayed elimination of loser cells when compared with azot WT flies.
Several long-lived mutant flies have displayed increased resistance to numerous stressors including oxidation, starvation and heat over wild-type flies, indicating a positive correlation between stress resistance and lifespan extension [ 6- 9].
Nevertheless, dj-1β mutant flies do not display decreased lifespan, which again is in contradiction with MFRTA.
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