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ept mutant eye clones were generated as described previously [4], [6].
Expression of exogenous rbf1 completely ablates ept mutant eye tissues but only mildly affects the development of discs composed of cells with wild type ept.
Also, as reported previously [33], the mutant eye phenotype of those rescued adults was suppressed somewhat (from 8% to 28% wild-type ommatidia) (Fig. 3D, J).
When we applied this technique to ESCRT-II mutants, the resulting mutant eye discs are overgrown compared to normal discs (Fig. 4).
The data presented here support a role for Stat92E in promoting cell division and to a lesser degree cell size in ept mutant eye disc cells.
We find that lowering stat92E gene dosage reduces expression of the epithelial polarity factor Crumbs (Crb) in ept mutant eye discs.
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Wild-type eyes and malS9 mutant eyes generated with the ey.flp/FRT Minute method were normally sized (Fig. 1I,J).
Expression of Slif (by means of ey-Gal4) slightly increased the sizes of control and PTEN mutant eyes, but this effect did not reach statistical significance (Author response image 3).
The models' latex cone heads and mutant eyes were a case of comic overkill; Mr. Takahashi's clothes expressed everything he had to say of the moment.
By checking how many offspring carried the mutant eye-color, they discovered that some males were better at sperm competition than others.
We have found that genetic reduction of the DaPKC apical-membrane kinase effectively suppress the growth of ept mutant eye-antennal tumors.
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