Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
First, we can examine glutamate receptors in DLG mutant embryos rather than larvae.
Similar(58)
None of these cell types showed any increase in their number compared with wt (Supplementary Figure S3; Figure 4e), suggesting DAC-positive neurons in puc mutant embryos are rather eliminated through cell death.
While embryonic patterning was rather normal in γCOP mutant embryos (see also below), they were smaller than wild type embryos and displayed weakly pigmented cuticles with poorly differentiated denticles (Figure 3); some of the mutants also displayed a partial dorsal open phenotype.
Because of this accelerated loss of the compound double mutant animals before weaning, we analyzed the NMJ in E18.5 embryos rather than in adults, as normal Mendelian distribution was observed at E18.5 in these mice (data not shown).
The severe shortening of segments and poorly defined segment boundaries observed in all mutant embryos suggest that the mutations affect the structure of each segment, rather than their establishment, possibly by interfering with the normal function of segment polarity genes.
In comparison with foscrb, which completely rescued the cuticle phenotype, crb mutant embryos carrying two copies of foscrb Y10A form continuous anterior and ventral cuticle with rather fully developed denticle belts.
Interestingly, Sox10-positive cells were observed at the dorsal entry zone and the motor exit point of both mutants at E12.5, suggesting that specification of BCCs rather than localization of their precursors was affected in β-catenin mutant embryos (Additional file 1: Figure S6D-I).
(G) Quantification of vacuoles in wild-type and mutant embryos.
We found biallelic mutant embryos and pups, indicating 100% efficiency in base conversion.
In this study, we successfully observed this phenomenon in Rab10 mutant embryos.
The ap2 mutant embryos are larger and have increased cell numbers and cell size.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com