Sentence examples for mutant embryos including from inspiring English sources

At this stage, defects are observed in brain development of kto mutant embryos, including a severely distorted midbrain (Figure 1A D).

Furthermore, MRI and 3D reconstruction of control and NKO mutant hearts at E13 revealed severe cardiovascular defects in NKO mutant embryos, including VSD and right ventricular outflow tract (RVOT) and a markedly dilated CAT that appeared to be formed by inclusion of all segments of the OFT and proximal parts of the pharyngeal arch arteries.

Of these genes, almost all were strongly reduced or absent in fd3F mutant embryos, including inner-arm dyneins Dhc16F (human DNAH6) and Dhc62B (DNaxonemalaxonemal dynein light chains CG8800 (DNAL1) and CG34192 (DNAlight-intermediatemediate chain CG6971 (DNALI1), and intermediate chain CG13930 (IC138, WDR78).

In a previous study we described in detail the phenotype of sall mutant embryos, which includes several landmarks of degeneration, such as fragility of the nervous tissue, deficient axonal cytoskeleton, loss of cell adhesion, enlarged extracellular space, vacuolization and abundant membrane "whorls" and autophagosomes [ 13].

In the ral1 mutant, the basal structures of the embryo, including the mesocotyl and radicle, are missing [80].

Expression of the shits mutant form of dynamin resulted in developmental consequences in the embryo, including disrupted metaphase furrows and loss of PM compartmentalization across the embryo.

BicD mutant embryos exhibited severe developmental defects including the loss of positional information defining the anterior region of the embryo and thereby giving rise to bicaudal embryos.

Founder males were further out-crossed, and then mated to their daughters to produce litters that would include homozygous mutant embryos.

Strikingly, embryonic lethal Fak56D-Dcas double mutant embryos had extensive cell polarity defects, including mislocalization and reduced expression of E-cadherin.

Mutant embryos displayed defects in anterior patterning, including abnormal head fold morphology, and abnormal neural groove (Fig. 3C,E).

We could detect genes that were consistently down-regulated in replicate pools of mutant embryos versus wild-type, and these included a number of known node and DE markers.